Johns Hopkins HIV Guide
G-CSF
INDICATIONS
FDA
FDA
- Chemotherapy-induced neutropenia in patients with cancer
- Neutropenia following bone marrow transplantation
- Mobilization of hematopoietic progenitor cells for collection by leukopheresis
- Idiopathic, cyclic or congenital neutropenia
- Increase survival in patients acutely exposed to myelosuppressive doses of radiation (Hematopoietic Syndrome of Acute Radiation Syndrome)
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Severe neutropenia associated with HIV and/or opportunistic infections
- Drug-induced neutropenia (AZT, ganciclovir, pyrimethamine, TMP/SMX and others)
- Prolonged neutropenia/immune effector cell-associated hematologic toxicity (ICAHT) after CAR T-cell therapy (not recommended within 14 days of infusion per NCCN due to theoretical cytokine release syndrome risk).
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Last updated: September 16, 2026
Citation
Soto, Caitlin, and Kathryn Dzintars. "G-CSF." Johns Hopkins HIV Guide Johns Hopkins HIV Guide, The Johns Hopkins University, 2026. Johns Hopkins Guides, www.hopkinsguide.org/hopkins/view/Johns_Hopkins_HIV_Guide/545263/all/G_CSF.
Soto C, Dzintars K. G-CSF. Johns Hopkins HIV Guide Johns Hopkins HIV Guide. The Johns Hopkins University; 2026. https://www.hopkinsguide.org/hopkins/view/Johns_Hopkins_HIV_Guide/545263/all/G_CSF. Accessed October 5, 2026.
Soto, C., & Dzintars, K. (2026). G-CSF. In Johns Hopkins HIV Guide Johns Hopkins HIV Guide. The Johns Hopkins University. https://www.hopkinsguide.org/hopkins/view/Johns_Hopkins_HIV_Guide/545263/all/G_CSF
Soto C, Dzintars K. G-CSF [Internet]. In: Johns Hopkins HIV Guide Johns Hopkins HIV Guide. The Johns Hopkins University; 2026. [cited 2026 October 05]. Available from: https://www.hopkinsguide.org/hopkins/view/Johns_Hopkins_HIV_Guide/545263/all/G_CSF.
* Article titles in AMA citation format should be in sentence-case
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UR - https://www.hopkinsguide.org/hopkins/view/Johns_Hopkins_HIV_Guide/545263/all/G_CSF
PB - The Johns Hopkins University
DB - Johns Hopkins Guides
DP - Unbound Medicine
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